Innovative Wound-Healing Technology from Red Ivy Plant
Research and Development
Researchers at the Jawaharlal Nehru Tropical Botanic Garden & Research Institute (JNTBGRI) have developed a multifunctional wound-healing pad using the red ivy plant, Strobilanthes alternata, known locally as "murikooti pacha."
Key Component: Acteoside
- Acteoside is a natural compound found in many plants, known for its pharmacological activities and therapeutic potential.
- This is the first instance of linking acteoside to the red ivy plant.
- The molecule shows high efficacy even at a low concentration of 0.2%.
Wound-Healing Pad Composition
- The pad features a multi-layered design:
- First layer: Prevents microbial growth and accelerates healing.
- Second layer: Absorbs wound exudate.
- Third layer: Absorbs and prevents odors.
- Incorporates neomycin sulfate and FDA-approved polymers.
- Employs a porous electro-spun nanofiber layer for optimal gas exchange.
- Includes a super absorbent sponge crafted from sodium alginate and an activated carbon layer.
Testing and Approval
- The biomaterials comply with ISO 10993-23: 2021 (E), a standard for the biological evaluation of medical devices.
- Animal studies have demonstrated significant wound healing acceleration.
- Tests confirm that the components do not cause genotoxicity, hypersensitivity, skin irritation, or inflammation.
Potential and Patent
- No similar multifunctional wound dressing pad is currently available in India.
- Materials are affordable and widely accessible for large-scale production.
- A provisional patent for the manufacturing process has been filed.
Collaboration and Support
This development was a collaborative effort by scientists including V. Gayathri, S. Ajikumaran Nair, B. Sabulal, Neeraja S. Raj, and V. Arunachalam, supported by the Kerala State Council for Science, Technology and Environment (KSCSTE) through its program, SHRESTA.
