Djibouti releases Genetically Modified (GM) Mosquitoes to fight Malaria | Current Affairs | Vision IAS
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    Djibouti releases Genetically Modified (GM) Mosquitoes to fight Malaria

    Posted 29 May 2024

    2 min read

    The release is part of the ‘Djibouti Friendly Mosquito Programme’ to stop the spread of Anopheles stephensi

    • Anopheles stephensi is a mosquito species that is capable of transmitting both Plasmodium falciparum and P. vivax malaria parasites.
    • Only female mosquitoes bite and transmit malaria and other viral diseases.

    Under the project, friendly non-biting male Anopheles stephensi mosquitoes have been developed and they carry self-limiting genes that kills female offspring before they reach maturity.

    • By reducing the female mosquito population, spread of the disease can be controlled.  

    Technology involved in creating GM Mosquitoes

    • Laboratory Method: GM mosquitoes are mass-produced in a laboratory to carry two types of genes:
      • A self-limiting gene that prevents female mosquito offspring from surviving to adulthood.
        • Similar technology has been successfully used in India.
      •  A fluorescent marker gene that glows under a special red light. 
    • Gene Drives Technology (GDT): A type of genetic engineering technique that modifies genes so that they don’t follow the typical rules of heredity.
      • It increases the likelihood that a particular suite of genes will be passed onto the next generation, allowing the genes to rapidly spread through a population and override natural selection.

    Key components of GDT

    • Gene to be spread
    • Cas9 enzyme that can cut DNA (acts as a molecular scissor)
    • Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR), a prommable DNA sequence that identifies where the enzyme should cut.

     

    • Tags :
    • GM Mosquito
    • Gene Drives Technology
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