World Economic Forum launched Davos Compact on Antimicrobial Resistance(AMR) 2025 | Current Affairs | Vision IAS

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In Summary

  • The Compact aims to secure sustainable financing to reduce global AMR deaths, potentially saving over 100 million lives by 2050.
  • AMR occurs when pathogens resist antimicrobial medicines, accelerated by human misuse of antimicrobials; India loses around 6 lakh lives annually due to resistant infections.
  • India's initiatives include National Action Plan on AMR 2.0, launching indigenous antibiotic Nafithromycin, and national surveillance networks; global efforts involve the GAP on AMR and UN High-Level Meeting.

In Summary

The Compact, supported by Unified Coalition for AMR Response aims to unlock sustainable financing from both public and private sources to reduce the global AMR deaths, saving more than 100 million lives by 2050.

About AMR

  • It occurs when bacteria, viruses, fungi and parasites no longer respond to antimicrobial medicines (antibiotics, antivirals, antifungals, etc.) making them ineffective.  
  • It is a natural process that happens over time through genetic changes in pathogens.
    • However, its spread is accelerated by human activity, mainly the misuse and overuse of antimicrobials. 
  • Status in India: Around 6 lakh lives are lost each year due to resistant infections. 

Key Initiatives taken to address AMR

  • National Action Plan on AMR 2.0 (2025-2029): Unified and coordinated effort across the human, animal, agriculture  and environmental sectors.
  • First Indigenous Antibiotic, Nafithromycin: Launched in 2024 ,it is  designed to treat both typical and atypical drug-resistant bacteria.
  • National surveillance networks: Generate annual AMR surveillance reports, with data submitted to the Global AMR Surveillance System (GLASS).
  • Global Initiatives Efforts: 
    • Global Action Plan (GAP) on AMR during 2015 World Health Assembly. 
    • United Nations General Assembly High-Level Meeting on AMR, 2024, to reduce global deaths associated with bacterial AMRs by 10% by 2030 against the 2019 baseline, etc.
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RELATED TERMS

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Global Action Plan (GAP) on AMR

A strategic framework developed by the World Health Organization (WHO) and other international bodies to coordinate global efforts in combating Antimicrobial Resistance (AMR).

Global AMR Surveillance System (GLASS)

A World Health Organization (WHO) initiative that standardizes and coordinates the collection and analysis of data on antimicrobial resistance and antimicrobial consumption worldwide, supporting national surveillance efforts.

Nafithromycin

India's first indigenous antibiotic, launched in 2024, designed to treat infections caused by both common and drug-resistant bacteria.

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