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Unified Genomic Chip

Posted 14 Nov 2024

Updated 18 Nov 2024

4 min read

Why in the News? 

Prime Minister launched Unified Genomic Chip and indigenous sex-sorted semen technology for the benefit of livestock in India

This image provides a brief definition of the term "Genomics." It states that genomics is the study of all of an organism's genes (the genome), including the interactions of those genes with each other and with the environment.

About Unified Genomic Chip 

  • It is a Single Nucleotide Polymorphism (SNP) chip. 
  • Objective: Designed for genomic profiling and evaluation of Indian cattle breeds. 
    • It has enabled the direct application of DNA technologies to enhance the genetic potential (genetic improvement) of diverse dairy animal populations in the country. 
    • These chips will help farmers to identify high-quality cattle early and enhance dairy farming efficiency.
  • Variants of the chip
    • Gau chip for cattle 
    • Mahish chip for buffaloes
  • Developed by: Consortium led by the Department of Animal Husbandry and Dairying (DAHD), Ministry of Animal Husbandry, Dairying and Fisheries.
    • It comprises of National Dairy Development Board (NDDB), National Institute of Animal Biotechnology (NAIB), etc.

About Single Nucleotide Polymorphisms (SNPs)

  • It refers to a variation in a DNA sequence where a single nucleotide is different from the reference sequence.
    • DNA sequences are formed from a chain of four nucleotide bases: Adenine (A), Cytosine (C), Guanine (G), and Thymine (T).
    • An SNP may replace the nucleotide Guanine (G) with the nucleotide thymine (T) in a certain stretch of DNA.
  • These are the most common type of genetic variation among people
  • They are commonly used in research studies and by genetic testing companies.
This image explains Single Nucleotide Polymorphisms (SNPs), which are variations at a single nucleotide position in the DNA sequence among individuals. It contrasts the standard DNA sequence found in the general population with an altered sequence showing an SNP, highlighting the change from "G" to "T" in the nucleotide sequence.

About Sex-sorted Semen Technology 

  • Sex Sorted Semen is the 'gender selected' semen used in Artificial Insemination (AI) for cattle and buffaloes.
  • It ensures the birth of only female calves with more than 90% accuracy whereas conventional semen produces equal proportion of male and female (50:50) calves. 
  • Under the 'Make in India' and 'Atmanirbhar Bharat' initiative, the NDDB has developed the indigenous technology of sex sorted semen. 
    • Till now it was manufactured by multinational companies.

About Genetic/Breed Improvement 

  • It involves selecting animals with superior traits, producing frozen semen, and disseminating it in the respective breeding tracts, in order to increase productivity of dairy animals.
    • It also promotes conservation of indigenous breeds. 
  • It involves different techniques such as Artificial Insemination, In-Vitro Fertilization (IVF), Embryo transfer technology (ETT), etc. 
  • Need for Genetic/Breed Improvement:
    • Building a disease-free closed herd
    • Developing climate-tolerant and disease-resistant breeds.
    • Contributes to the overall genetic pool of the breed, ensuring long-term sustainability.
    • Empowering farmers and building resilient livelihoods.
    • Reducing dependence over exotic species and cross breeds.

Other Initiatives Taken by India for Genetic/Breed Improvement

  • Rashtriya Gokul Mission (2014): Launched with the aim of development and conservation of indigenous bovine breeds and genetic upgradation of bovine population.  Under it, following initiatives have been taken 
    • Implementation of Nationwide Artificial Insemination Programme
    • Accelerated breed improvement programme using bovine In-Vitro Fertilization technology (IVF)
    • Progeny Testing and Pedigree Selection Programme to produce high genetic merit bulls.
    • Delivery of quality artificial insemination services at farmers doorstep through Multi Purpose Artificial Insemination Technicians in Rural India (MAITRIs). 
    • Establishment of breed multiplication farm.
The image defines Germplasm as the genetic material of an individual from one generation to another.
  • IndiGau: India’s first Cattle Genomic Chip for the conservation of pure varieties of indigenous cattle breeds like, Gir, Kankrej, Sahiwal, Ongole etc.
    • Launched by NAIB (under the aegis of the Department of Biotechnology).
  • Other initiatives
    • Breed improvement under National Livestock Mission (NLM), 2014.
    • e-pashuhaat Portal for connecting breeders and farmers regarding availability of bovine germplasm.
    • Information Network for Animal Productivity and Health (INAPH): Developed by NDDB, facilitates capturing of real time reliable data on Breeding, Nutrition and Health Services. 
The image illustrates four major challenges associated with the process of Genetic Improvement. This includes Availability of little information on the performance status of cattle breeds in their native environment, Requirement of five to six generations to upgrade the level of improved breed, Absence of breeder organisations/programmes for each breed and Lack of Semen production centres and research institutes.

Conclusion 

Launch of Unified Genomic Chip for cattle and indigenous sex-sorted semen technology will help in improving the genetic potential and productivity of the cattle and increase in farmers’ income. Also, it will support food security of the country. 

Important Indigenous Cattle/Buffaloes Breeds

Cattle 

Breed 

Breeding Tract

Gir and Kankrej

Gujarat 

Tharparkar and Sahiwal 

Punjab and Rajasthan

Badri 

Uttarakhand

Deoni, Dangi and Khillari

Maharashtra

Ongole 

Andhra Pradesh

Buffalo

Breed

Breeding Tract

Banni and Jaffarabadi

Gujarat

Bhadawari

Uttar Pradesh and Madhya Pradesh

Murrah

Haryana and Delhi

Mehsana

Gujarat and Maharashtra

  • Tags :
  • Unified Genomic Chip
  • Genomic Chip
  • Single Nucleotide Polymorphisms (SNPs)
  • Genetic/Breed Improvement
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