Initiative aims to publicly release a fully annotated bacteriological genome, enhancing scientific knowledge, driving innovation, and making microbial genomics data accessible to researchers and the community.
About Genome and Genome Sequencing
- Genome: Complete set of genetic material (deoxyribonucleic acid or DNA/ ribonucleic acid or RNA) containing an organism's entire hereditary information, composed of unique nucleotide base sequences.
- Genomic Sequencing: The process of determining the precise order of nucleotide bases (adenine (A), cytosine (C), guanine (G), and thymine (T) in DNA; A, C, G, uracil (U) in RNA) within an organism's genetic material.
Applications of Genome Sequencing (GS)
- Disease detection: To evaluate rare disorders, preconditions for disorders. E.g., Cystic fibrosis and thalassemia.
- Pharmacogenomics: Involves evaluating effectiveness & safety of drugs on the basis of information from an individual's GS.
- Metagenomic Sequencing: Explores collective genomes of multiple species in an environmental niche, enabling rapid species identification and environmental impact analysis.
- Agriculture: Identify genetic markers for disease resistance and drought tolerance in various crop plants; reduced time to develop new varieties of crop plants; decipher the host-pathogen relationships in crops.
- Microbial Sequencing: It enables advanced biofuel development, innovative diagnostic tools, improved vaccines, and sophisticated environmental cleanup techniques.
Significance of Microbes
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